Leriche Syndrome

What is Leriche Syndrome?
Leriche Syndrome is a condition that manifests symptoms because of a blockage in arterial blood
flow. This arterial occlusion is noted at the area of bifurcation, or division, of your aorta and common
iliac arteries. Usually, this blockage is due to a plaque buildup, also known as atherosclerosis.
Leriche Syndrome can be categorized into three different classifications: Type 1 (atherosclerosis of
distal abdominal aorta and common iliac arteries), Type 2 (atherosclerosis of distal abdominal aorta,
common iliac arteries, and external iliac arteries), Type 3 (atherosclerosis of aortoiliac segment and
femoropopliteal vessels). To diagnose this condition, your physician may perform screening tests,
such as an ankle-brachial index test (ABI). An ABI less than 0.9 indicates that your legs and feet are
not receiving as much blood flow as required. Also, duplex ultrasonography or CTA may be used to
pinpoint the specific location of occlusion.

What are the symptoms?
Patients with arterial blockage may have no symptoms. However, the most common symptoms for
patients with Leriche Syndrome include hip, thigh, and buttock claudication which may be on both
sides. Claudication is described as a cramping pain that is exacerbated by exercise. Another crucial
aspect of Leriche syndrome is impotence, which is the inability to achieve an erection or orgasm. In
fact, sexual dysfunction is so often associated with Leriche Syndrome that the absence of this
symptom suggests that another diagnosis should be considered. In addition, muscle atrophy, or
breakdown, in your legs may result from this chronic arterial blockage. Your physician may also tell
you, after examination, that your femoral pulses are diminished or absent due to the disrupted flow
of blood.

Who is at risk?
Men with atherosclerosis are especially at high risk for Leriche Syndrome. Women are less likely to
develop this condition in comparison to men. Patients who have a predisposition to atherosclerosis
are generally considered to be at higher risk for this condition, and there are several modifiable risk
factors for plaque buildup. Atherosclerosis is potentiated by hypertension, smoking, lower physical
activity, obesity, a diet high in saturated fats, and high glucose or lipid levels.

What are the treatment options?
If no treatment is pursued, a poor prognosis with worsening symptoms is more likely. Treatment is
patient-specific and based on age, health, and severity. There are several options for treatment, and
these management choices may help slow the progression of symptoms. First, it is recommended
that all patients who have risk factors for atherosclerosis treat or alter relating lifestyle choices.
Exercise programs have been shown to decrease walking restrictions. Surgical treatments for
Leriche Syndrome include aortobifemoral bypass, percutaneous transluminal angioplasty, and
thromboendarterectomy. Aortobifemoral bypass, which redirects blood around the blocked blood
vessels, has been shown to have the best blood flow rates with patency in patients who are able to
tolerate the procedure. Imaging studies may also be ordered and help your physician determine the
likelihood of successful surgery and possible complications. Finally, a medication called Cilostazol is
occasionally prescribed to help with symptoms of cramping.
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